ALDH2, aldehyde dehydrogenase 2 family member, 217

N. diseases: 287; N. variants: 18
Disease: Ischemic stroke ×
Source: BEFREE ×
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0948008
Disease: Ischemic stroke
Ischemic stroke 		0.150 GeneticVariation disease BEFREE <b>Conclusion:</b> Our meta-analysis indicates that the <i>ALDH2</i> rs671 G>A polymorphism may play an important role in the occurrence of IS by reducing the activity of ALDH2 and interfering with the metabolic processes involving acetaldehyde. 31114208 2019
CUI: C0948008
Disease: Ischemic stroke
Ischemic stroke 		0.150 AlteredExpression disease BEFREE In conclusion, increasing ALDH2 activity can improve brain edema, infarct volumes, and reduce neurological impairment in a rat IS model. 29767275 2018
CUI: C0948008
Disease: Ischemic stroke
Ischemic stroke 		0.150 GeneticVariation disease BEFREE Genetic variants in ALDH2 predict risk of ischemic stroke in a Chinese population. 30077765 2018
CUI: C0948008
Disease: Ischemic stroke
Ischemic stroke 		0.150 GeneticVariation disease BEFREE This study intended to further investigate whether the above variant of ALDH2 increases the risk for ischemic stroke in Taiwanese. 27486170 2016
CUI: C0948008
Disease: Ischemic stroke
Ischemic stroke 		0.150 Biomarker disease BEFREE ALDH2(*)2 could be a protective factor and negative predictor for severe intracranial vascular stenosis in ischemic stroke in Han Chinese. 26000808 2016