FABP5, fatty acid binding protein 5, 2171

N. diseases: 85; N. variants: 1
Disease: Pain ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0030193
Disease: Pain
Pain 		0.030 Biomarker phenotype BEFREE Fatty acid binding protein 5 (FABP5) is a promising target for development of inhibitors to help control pain and inflammation. 31539229 2019
CUI: C0030193
Disease: Pain
Pain 		0.030 Biomarker phenotype BEFREE PGE<sub>2</sub> is a major eicosanoid that enhances pain in the setting of inflammation, and we focused on the mechanism(s) through which FABP5 modulates PGE<sub>2</sub> production. 29440395 2018
CUI: C0030193
Disease: Pain
Pain 		0.030 AlteredExpression phenotype BEFREE Although FABP5 and TRPV1 were co-expressed in the periaqueductal gray region of the brain, which is known to modulate pain, knockdown of FABP5 in the periaqueductal gray using adeno-associated viruses and pharmacological FABP5 inhibition did not produce analgesic effects. 28326944 2017