Obesity
|
0.520 |
AlteredExpression
|
disease |
BEFREE |
Consistent with the cell culture system, muscle-specific SENP2 overexpression led to a marked increase in the mRNA levels of CPT1b and ACSL1 and thereby in FAO in the skeletal muscle, which ultimately alleviated high-fat diet-induced obesity and insulin resistance.
|
25784542 |
2015 |
Obesity
|
0.520 |
Biomarker
|
disease |
CTD_human |
Orchestrated downregulation of genes involved in oxidative metabolic pathways in obese vs. lean high-fat young male consumers.
|
20882379 |
2011 |
Obesity
|
0.520 |
Biomarker
|
disease |
BEFREE |
We quantified mRNA expression of subcutaneous adipose tissue fatty-acid-handling proteins (ALBP, KLBP, FATP1, FATP4, CD36, ACS1) in 17 monozygotic twin-pairs with a range of intra-pair differences (Delta) in BMI and detailed measures of obesity and insulin resistance, allowing influences of genetic and non-genetic factors to be distinguished.
|
15168018 |
2004 |
Obesity
|
0.520 |
Biomarker
|
disease |
RGD |
Marked enhancement of acyl-CoA synthetase activity and mRNA, paralleled to lipoprotein lipase mRNA, in adipose tissues of Zucker obese rats (fa/fa).
|
1543733 |
1992 |
Hepatitis, Toxic
|
0.300 |
Biomarker
|
disease |
CTD_human |
Characteristic molecular and proteomic signatures of drug-induced liver injury in a rat model.
|
25231249 |
2015 |
Drug-Induced Liver Disease
|
0.300 |
Biomarker
|
phenotype |
CTD_human |
Characteristic molecular and proteomic signatures of drug-induced liver injury in a rat model.
|
25231249 |
2015 |
Hepatitis, Drug-Induced
|
0.300 |
Biomarker
|
disease |
CTD_human |
Characteristic molecular and proteomic signatures of drug-induced liver injury in a rat model.
|
25231249 |
2015 |
Drug-Induced Acute Liver Injury
|
0.300 |
Biomarker
|
disease |
CTD_human |
Characteristic molecular and proteomic signatures of drug-induced liver injury in a rat model.
|
25231249 |
2015 |
Chemical and Drug Induced Liver Injury
|
0.300 |
Biomarker
|
disease |
CTD_human |
Characteristic molecular and proteomic signatures of drug-induced liver injury in a rat model.
|
25231249 |
2015 |
Chemically-Induced Liver Toxicity
|
0.300 |
Biomarker
|
disease |
CTD_human |
Characteristic molecular and proteomic signatures of drug-induced liver injury in a rat model.
|
25231249 |
2015 |
Liver Cirrhosis, Experimental
|
0.300 |
Biomarker
|
disease |
CTD_human |
Systems level analysis and identification of pathways and networks associated with liver fibrosis.
|
25380136 |
2014 |
Arthritis, Adjuvant-Induced
|
0.300 |
Biomarker
|
disease |
CTD_human |
Impaired intrinsic chiral inversion activity of ibuprofen in rats with adjuvant-induced arthritis.
|
18988084 |
2008 |
Arthritis, Collagen-Induced
|
0.300 |
Biomarker
|
disease |
CTD_human |
Impaired intrinsic chiral inversion activity of ibuprofen in rats with adjuvant-induced arthritis.
|
18988084 |
2008 |
Arthritis, Experimental
|
0.300 |
Biomarker
|
disease |
CTD_human |
Impaired intrinsic chiral inversion activity of ibuprofen in rats with adjuvant-induced arthritis.
|
18988084 |
2008 |
Carcinoma
|
0.300 |
Biomarker
|
group |
CTD_human |
Global gene expression profiling of chemically induced rat mammary gland carcinomas and adenomas.
|
16316942 |
2005 |
Animal Mammary Neoplasms
|
0.300 |
Biomarker
|
phenotype |
CTD_human |
Global gene expression profiling of chemically induced rat mammary gland carcinomas and adenomas.
|
16316942 |
2005 |
Mammary Neoplasms, Experimental
|
0.300 |
Biomarker
|
phenotype |
CTD_human |
Global gene expression profiling of chemically induced rat mammary gland carcinomas and adenomas.
|
16316942 |
2005 |
Anaplastic carcinoma
|
0.300 |
Biomarker
|
disease |
CTD_human |
Global gene expression profiling of chemically induced rat mammary gland carcinomas and adenomas.
|
16316942 |
2005 |
Carcinoma, Spindle-Cell
|
0.300 |
Biomarker
|
disease |
CTD_human |
Global gene expression profiling of chemically induced rat mammary gland carcinomas and adenomas.
|
16316942 |
2005 |
Undifferentiated carcinoma
|
0.300 |
Biomarker
|
disease |
CTD_human |
Global gene expression profiling of chemically induced rat mammary gland carcinomas and adenomas.
|
16316942 |
2005 |
Carcinomatosis
|
0.300 |
Biomarker
|
phenotype |
CTD_human |
Global gene expression profiling of chemically induced rat mammary gland carcinomas and adenomas.
|
16316942 |
2005 |
Mammary Carcinoma, Animal
|
0.300 |
Biomarker
|
disease |
CTD_human |
Global gene expression profiling of chemically induced rat mammary gland carcinomas and adenomas.
|
16316942 |
2005 |
Alloxan Diabetes
|
0.300 |
Biomarker
|
disease |
CTD_human |
Troglitazone lowers islet fat and restores beta cell function of Zucker diabetic fatty rats.
|
9452481 |
1998 |
Diabetes Mellitus, Experimental
|
0.300 |
Biomarker
|
disease |
CTD_human |
Troglitazone lowers islet fat and restores beta cell function of Zucker diabetic fatty rats.
|
9452481 |
1998 |
Streptozotocin Diabetes
|
0.300 |
Biomarker
|
disease |
CTD_human |
Troglitazone lowers islet fat and restores beta cell function of Zucker diabetic fatty rats.
|
9452481 |
1998 |