Body Height
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
|
30595370 |
2019 |
Influenza due to Influenza A virus subtype H1N1
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
No Major Host Genetic Risk Factor Contributed to A(H1N1)2009 Influenza Severity.
|
26379185 |
2015 |
Blepharoptosis
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Saethre-Chotzen syndrome (acrocephalo-syndactyly type III, ACS III) is an autosomal dominant craniosynostosis with brachydactyly, soft tissue syndactyly and facial dysmorphism including ptosis, facial asymmetry and prominent ear crura.
|
8988167 |
1997 |
Craniosynostosis
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Saethre-Chotzen syndrome (acrocephalo-syndactyly type III, ACS III) is an autosomal dominant craniosynostosis with brachydactyly, soft tissue syndactyly and facial dysmorphism including ptosis, facial asymmetry and prominent ear crura.
|
8988167 |
1997 |
Glioma
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
The lower fatty acyl pool may be mediated by the lower protein expression levels of long-chain acyl-CoA synthetase 1 (ACSL1), ACSL4, and very long-chain acyl-CoA synthetase 3 (ACSVL3) in IDH1 mutant glioma.
|
30596429 |
2019 |
Ptosis
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Saethre-Chotzen syndrome (acrocephalo-syndactyly type III, ACS III) is an autosomal dominant craniosynostosis with brachydactyly, soft tissue syndactyly and facial dysmorphism including ptosis, facial asymmetry and prominent ear crura.
|
8988167 |
1997 |
Syndactyly
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Saethre-Chotzen syndrome (acrocephalo-syndactyly type III, ACS III) is an autosomal dominant craniosynostosis with brachydactyly, soft tissue syndactyly and facial dysmorphism including ptosis, facial asymmetry and prominent ear crura.
|
8988167 |
1997 |
Brachydactyly
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Saethre-Chotzen syndrome (acrocephalo-syndactyly type III, ACS III) is an autosomal dominant craniosynostosis with brachydactyly, soft tissue syndactyly and facial dysmorphism including ptosis, facial asymmetry and prominent ear crura.
|
8988167 |
1997 |
Congenital anomaly of face
|
0.010 |
GeneticVariation
|
group |
BEFREE |
Saethre-Chotzen syndrome (acrocephalo-syndactyly type III, ACS III) is an autosomal dominant craniosynostosis with brachydactyly, soft tissue syndactyly and facial dysmorphism including ptosis, facial asymmetry and prominent ear crura.
|
8988167 |
1997 |
Congenital facial asymmetry
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Saethre-Chotzen syndrome (acrocephalo-syndactyly type III, ACS III) is an autosomal dominant craniosynostosis with brachydactyly, soft tissue syndactyly and facial dysmorphism including ptosis, facial asymmetry and prominent ear crura.
|
8988167 |
1997 |
Diabetes Mellitus, Experimental
|
0.200 |
Biomarker
|
disease |
RGD |
Elevated expression of liver X receptor alpha (LXRα) in myocardium of streptozotocin-induced diabetic rats.
|
21136146 |
2011 |
Inflammation
|
0.200 |
Biomarker
|
phenotype |
RGD |
Up-regulation of fatty acid metabolizing-enzymes mRNA in rat spinal cord during persistent peripheral local inflammation.
|
14622223 |
2003 |
Malignant neoplasm of prostate
|
0.040 |
Biomarker
|
disease |
BEFREE |
Furthermore, we examined the role of ACSL3 in the androgen metabolism of prostate cancer.
|
28771887 |
2017 |
Prostate carcinoma
|
0.040 |
Biomarker
|
disease |
BEFREE |
Furthermore, we examined the role of ACSL3 in the androgen metabolism of prostate cancer.
|
28771887 |
2017 |
Asthma
|
0.020 |
Biomarker
|
disease |
BEFREE |
Thus, if validated, methylated ACSL3 5'CGI in UCWBC DNA may be a surrogate endpoint for transplacental PAH exposure and/or a potential biomarker for environmentally-related asthma.
|
19221603 |
2009 |
Asthma
|
0.020 |
Biomarker
|
disease |
BEFREE |
The aim of this study was to compare the mRNA expression patterns of Interleukin (IL)-4, interferon (IFN)-γ and Acyl Co A long chain 3 (ACSL3) in peripheral blood leukocytes of children with and without asthma.
|
24450480 |
2014 |
Malignant neoplasm of lung
|
0.020 |
Biomarker
|
disease |
BEFREE |
Finally, ACSL3 is essential for mutant KRAS lung cancer tumorigenesis in vivo and is highly expressed in human lung cancer.
|
27477280 |
2016 |
Carcinoma of lung
|
0.020 |
Biomarker
|
disease |
BEFREE |
Finally, ACSL3 is essential for mutant KRAS lung cancer tumorigenesis in vivo and is highly expressed in human lung cancer.
|
27477280 |
2016 |
Primary malignant neoplasm of lung
|
0.020 |
Biomarker
|
disease |
BEFREE |
Finally, ACSL3 is essential for mutant KRAS lung cancer tumorigenesis in vivo and is highly expressed in human lung cancer.
|
27477280 |
2016 |
Hormone refractory prostate cancer
|
0.020 |
Biomarker
|
disease |
BEFREE |
Interestingly, microarray analysis revealed that OCT1 regulates CRPC-specific target genes in addition to representative AR-regulated genes such as ACSL3.
|
30649323 |
2019 |
Malignant Neoplasms
|
0.010 |
Biomarker
|
group |
BEFREE |
Among the five family isoforms, ACSL1 and ACSL4 are able to promote ungoverned cell growth, facilitate tumor invasion and evade programmed cell death, while ACSL3 may have relatively complex functions in different types of cancer.
|
30008815 |
2018 |
Hepatitis C
|
0.010 |
Biomarker
|
disease |
LHGDN |
These results identify ACSL3 as a new enzymatic target to limit VLDL secretion and HCV infection.
|
18003621 |
2008 |
Hepatitis C
|
0.010 |
Biomarker
|
disease |
BEFREE |
These results identify ACSL3 as a new enzymatic target to limit VLDL secretion and HCV infection.
|
18003621 |
2008 |
Liver neoplasms
|
0.010 |
Biomarker
|
group |
BEFREE |
Long chain acyl-CoA synthetase 3-mediated phosphatidylcholine synthesis is required for assembly of very low density lipoproteins in human hepatoma Huh7 cells.
|
18003621 |
2008 |
melanoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
High ACSL3 expression predicted a better prognosis in ovarian cancer; in contrast, high ACSL3 predicted a worse prognosis in melanoma.
|
27171439 |
2016 |