PTK2B, protein tyrosine kinase 2 beta, 2185

N. diseases: 319; N. variants: 9
Disease: Hypertensive disease ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.220 PosttranslationalModification group BEFREE IMD could attenuate the vascular collagen remodeling caused by angiotensin II-induced hypertension via inhibiting phosphorylation of Akt and MAPK. 30229842 2018
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.220 Biomarker group RGD In the present study, we examined whether FAK and PYK2 are up-regulated by elevated blood pressure or circulating humoral factors in hypertension. 21068519 2010
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.220 GeneticVariation group LHGDN To examine the contribution of PTK2B, we sequenced the PTK2B gene using 48 patients with hypertension, identified 62 genetic polymorphisms, and genotyped six representative single nucleotide polymorphisms in population-based case-control samples from 3655 Japanese individuals (1520 patients with hypertension and 2135 controls). 18075463 2007