FASN, fatty acid synthase, 2194

N. diseases: 215; N. variants: 6
Disease: Apraxia, Developmental Verbal ×
Source: BEFREE ×
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0750927
Disease: Apraxia, Developmental Verbal
Apraxia, Developmental Verbal 		0.010 Biomarker disease BEFREE Patients with CAS had higher cFAS activity (p < 0.01), and patients with diabetes had higher cFAS activity than patients with no diabetes (p < 0.05). cFAS activity correlated with serum glucose (p = 0.03, r<sup>2</sup> = 0.35), and cFAS content trended with plaque FAS content (p = 0.06, r<sup>2</sup> = 0.69). cFAS was predominantly in LDL cholesterol fractions of patients with CAS (p < 0.001), and IP of cFAS demonstrated pulldown of ApoB. 31202106 2019