STOX1, storkhead box 1, 219736

N. diseases: 39; N. variants: 15
Disease: Hypertensive disease ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.130 Biomarker group BEFREE Alpha-1 microglobulin as a potential therapeutic candidate for treatment of hypertension and oxidative stress in the STOX1 preeclampsia mouse model. 31189914 2019
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.130 Biomarker group BEFREE Other genetic variants that may affect maternal blood pressure in pregnancy arise from the fetal genome, for example wild-type pregnant mice carrying offspring with Cdkn1c or Stox1 disrupted develop hypertension and proteinuria. 24842698 2014
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.130 GeneticVariation group BEFREE Mutations in STOX1 were proposed to be causal for predisposing to preeclampsia, a hypertensive disorder originating from placental defects, affecting up to 10% of human pregnancies. 19079545 2008
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.130 Biomarker group HPO