B-CELL MALIGNANCY, LOW-GRADE
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Together, these data confirm that CD23 protein is phosphorylated in B cells of B-CLL patients, report the identification of new CD23 phosphorylation sites, and suggest a possible role(s) of such phosphorylations in the activation of CD23 during the process of lymphocytic activation in B-CLL.
|
29763855 |
2018 |
B-CELL MALIGNANCY, LOW-GRADE
|
0.100 |
Biomarker
|
disease |
BEFREE |
B-cell chronic lymphocytic leukemia (B-CLL) results in an accumulation of mature CD5(+)/CD23(+) B cells due to an uncharacterized defect in apoptotic cell death.
|
19188704 |
2008 |
B-CELL MALIGNANCY, LOW-GRADE
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
These data indicate that downregulation of CD23 and loss of Notch2 activity are early steps in PI-induced apoptosis of B-CLL lymphocytes and may be part of the full apoptotic response.
|
15565166 |
2005 |
B-CELL MALIGNANCY, LOW-GRADE
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Regulation of CD23 expression by Notch2 in B-cell chronic lymphocytic leukemia.
|
15621797 |
2005 |
B-CELL MALIGNANCY, LOW-GRADE
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
B-cell chronic lymphocytic leukemia (B-CLL) is phenotypically characterized by cell surface co-expression of CD19, CD20, CD5, and CD23.
|
15370224 |
2004 |
B-CELL MALIGNANCY, LOW-GRADE
|
0.100 |
Biomarker
|
disease |
BEFREE |
We report a case of a patient with two B-cell lymphoproliferative disorders: CD5(-)/CD23(+) B-cell chronic lymphocytic leukemia and CD5(+)/CD23(-) mantle cell lymphoma.
|
12500296 |
2003 |
B-CELL MALIGNANCY, LOW-GRADE
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
The aim of this study was to elucidate the mechanisms leading to the overexpression of CD23, a striking feature of B-cell chronic lymphocytic leukemia (B-CLL) cells.
|
11986231 |
2002 |
B-CELL MALIGNANCY, LOW-GRADE
|
0.100 |
Biomarker
|
disease |
BEFREE |
B-cell chronic lymphocytic leukemia (B-CLL) is characterized by the accumulation of mature-appearing clonal B cells exhibiting coexpression of CD5 and CD23.
|
10861692 |
2000 |
B-CELL MALIGNANCY, LOW-GRADE
|
0.100 |
Biomarker
|
disease |
BEFREE |
B-cell chronic lymphocytic leukemia (B-CLL) is a slowly progressive disease characterized by the clonal expansion of CD5+/CD23+ B lymphocytes.
|
9192749 |
1997 |
B-CELL MALIGNANCY, LOW-GRADE
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Thus this rearrangement appears to be very rare in B-CLL and its finding should lead to a careful search for the characteristic features of MZL, namely, morphology, the expression of CD5 without CD23, high density monotypic SIg, together with t(11;14) and/or bcl-1/IgH rearrangement.
|
9250825 |
1997 |
B-CELL MALIGNANCY, LOW-GRADE
|
0.100 |
Biomarker
|
disease |
BEFREE |
A 59-year-old man was diagnosed to have B-cell chronic lymphocytic leukemia with typical morphology and immunophenotype (CD5+, CD19+, and CD23+).
|
9109943 |
1997 |
B-CELL MALIGNANCY, LOW-GRADE
|
0.100 |
Biomarker
|
disease |
BEFREE |
Immunophenotyping of 61 relevant cases using a selected panel of monoclonal antibodies (mAb), showed that CD1c and CD23 mAb were able to separate B-cell chronic lymphocytic leukaemia (B-CLL) from other chronic B-cell lymphoproliferative diseases.
|
1714406 |
1991 |