Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0036220
Disease: Kaposi Sarcoma
Kaposi Sarcoma
0.030 Biomarker disease BEFREE Examination of this powerful viral oncogene may expose novel targets for the treatment of patients with KS and could ultimately provide a unique perspective into how GPCRs, and specifically chemokine receptors, contribute to angiogenesis and tumorigenesis. 20213674 2010
CUI: C0036220
Disease: Kaposi Sarcoma
Kaposi Sarcoma
0.030 Biomarker disease BEFREE These data suggest that KS results in part from KSHV-GPCR induction of proinflammatory cytokine and growth factor gene expression, mediated by a signaling determinant within the last five amino acids of the C terminus, a domain that is also critical for direct cell transformation. 11418689 2001
CUI: C0036220
Disease: Kaposi Sarcoma
Kaposi Sarcoma
0.030 Biomarker disease BEFREE Mice transgenic for GPCR have a KS-like region in the skin. 11056556 2000