FGF2, fibroblast growth factor 2, 2247

N. diseases: 635; N. variants: 7
Disease: Malignant neoplasm of stomach ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach 		0.080 AlteredExpression disease BEFREE In summary, FGF2 expression was demonstrated to be an independent prognostic factor in GC, and higher levels of FGF2 may promote the progression of this malignancy. 31789423 2020
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach 		0.080 AlteredExpression disease BEFREE In conclusion, HTRA1 promotes transdifferentiation of normal fibroblasts to cancer-associated fibroblasts by increasing bFGF/FGF2 expression, which is dependent upon activation of NF-κB signaling in gastric cancer. 31088682 2019
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach 		0.080 AlteredExpression disease BEFREE Expression levels of miR-195-5p and bFGF showed negative correlation in human GC tissues. 28500362 2017
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach 		0.080 Biomarker disease BEFREE Fibroblast growth factor 2 (FGFR2) amplification, occurring in ~2-9% of gastric cancers (GC), is associated with poor overall survival. 28122360 2017
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach 		0.080 AlteredExpression disease BEFREE PVT1 was positively associated with CD151 and FGF2 expression in GC tissues. 28258379 2017
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach 		0.080 Biomarker disease BEFREE The FGF2-binding peptide derivative P32 has improved stability, is relatively safe, and may have therapeutic potential in FGF2-driven gastric cancer. 25894376 2015
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach 		0.080 AlteredExpression disease BEFREE HGF and bFGF mRNA expression can be used as useful parameters to evaluate the prognosis of gastric cancer. 19533745 2009
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach 		0.080 Biomarker disease BEFREE These results suggest that FGF-2 may play an important role for the growth of diffuse type gastric cancers, particularly at their advanced stage. 9490085 1997