FGF2, fibroblast growth factor 2, 2247

N. diseases: 635; N. variants: 7
Disease: Tumor-Associated Vasculature ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1519666
Disease: Tumor-Associated Vasculature
Tumor-Associated Vasculature 		0.020 Biomarker disease BEFREE We further discovered that the intratumoral accumulation of intravenously administrated fluorescein isothiocyanate-dextran of 2,000,000Da (2MDa) was significantly reduced in the FGF-2 co-administered tumors despite unaltered hyaluronan accumulation and pericyte coverage of the tumor neovasculature and increased lymphangiogenesis. 27080571 2016
CUI: C1519666
Disease: Tumor-Associated Vasculature
Tumor-Associated Vasculature 		0.020 Biomarker disease BEFREE Pretreated EPCs showed significantly upregulated surface alpha4 and alphaM integrin subunit expression involved in the homing of immature cells to a neovasculature and enhanced FGF-2 and promatrix metalloproteinase (MMP)-2 secretion. 18239152 2008