|
AMYOTROPHIC LATERAL SCLEROSIS 1
|
0.300 |
Biomarker
|
disease |
CTD_human |
Differential expression of inflammation- and apoptosis-related genes in spinal cords of a mutant SOD1 transgenic mouse model of familial amyotrophic lateral sclerosis.
|
11796754 |
2002 |
|
Amyotrophic Lateral Sclerosis, Sporadic
|
0.300 |
Biomarker
|
disease |
CTD_human |
Differential expression of inflammation- and apoptosis-related genes in spinal cords of a mutant SOD1 transgenic mouse model of familial amyotrophic lateral sclerosis.
|
11796754 |
2002 |
|
Amyotrophic Lateral Sclerosis, Familial
|
0.300 |
Biomarker
|
disease |
CTD_human |
Differential expression of inflammation- and apoptosis-related genes in spinal cords of a mutant SOD1 transgenic mouse model of familial amyotrophic lateral sclerosis.
|
11796754 |
2002 |
|
Degenerative polyarthritis
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Here, we review the involvement of FGFs in bone-related processes and diseases; FGF1 in the differentiation of human bone marrow mesenchymal stem cells and fracture repair; FGF2, FGF9, and FGF18 in osteoarthritis; FGF6 in bone and muscle injury; FGF8 in osteoarthritis and Kashin-Beck disease; and FGF21 and FGF23 on bone regulation.
|
31260189 |
2019 |
|
Systemic Scleroderma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
In addition, FGF6 downregulation correlated with iron-metabolism dysfunction in systemic sclerosis and cancer cells.
|
30814063 |
2019 |
|
Intraductal papillary mucinous neoplasm
|
0.010 |
Biomarker
|
disease |
BEFREE |
Alterations in FGF23, CCND2, PIK3CA, and FGF6 were more commonly detected in intraductal papillary mucinous neoplasm-associated PDACs.
|
30836094 |
2019 |
|
Mental condensation
|
0.010 |
Biomarker
|
disease |
BEFREE |
Shugoshin and the deacetylase Hst2 facilitated spreading the condensation signal to the chromosome arms.
|
30318142 |
2018 |
|
Neuroblastoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
Remarkably, such hypomethylation affected cancer-related biological functions and genes relevant to NB pathogenesis such as CCND1, SPRR3, BTC, EGF and FGF6.
|
23144874 |
2012 |
|
Central neuroblastoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
Remarkably, such hypomethylation affected cancer-related biological functions and genes relevant to NB pathogenesis such as CCND1, SPRR3, BTC, EGF and FGF6.
|
23144874 |
2012 |
|
Childhood Neuroblastoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
Remarkably, such hypomethylation affected cancer-related biological functions and genes relevant to NB pathogenesis such as CCND1, SPRR3, BTC, EGF and FGF6.
|
23144874 |
2012 |
|
Malignant Neoplasms
|
0.010 |
Biomarker
|
group |
BEFREE |
Data from lymphoma and colorectal cancer samples for SNRPN (imprinted gene), FGF6 (demethylated in the cancer samples) and HS3ST2 (methylated in the cancer samples) serve as a proof of principle showing the integration of SNP data and phased DNA-methylation information into "hepitypes" and thus the analysis of DNA methylation phylogeny in the somatic evolution of cancer.
|
21750708 |
2011 |
|
Lymphoma
|
0.010 |
Biomarker
|
group |
BEFREE |
Data from lymphoma and colorectal cancer samples for SNRPN (imprinted gene), FGF6 (demethylated in the cancer samples) and HS3ST2 (methylated in the cancer samples) serve as a proof of principle showing the integration of SNP data and phased DNA-methylation information into "hepitypes" and thus the analysis of DNA methylation phylogeny in the somatic evolution of cancer.
|
21750708 |
2011 |
|
Primary malignant neoplasm
|
0.010 |
Biomarker
|
group |
BEFREE |
Data from lymphoma and colorectal cancer samples for SNRPN (imprinted gene), FGF6 (demethylated in the cancer samples) and HS3ST2 (methylated in the cancer samples) serve as a proof of principle showing the integration of SNP data and phased DNA-methylation information into "hepitypes" and thus the analysis of DNA methylation phylogeny in the somatic evolution of cancer.
|
21750708 |
2011 |
|
Adult Lymphoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
Data from lymphoma and colorectal cancer samples for SNRPN (imprinted gene), FGF6 (demethylated in the cancer samples) and HS3ST2 (methylated in the cancer samples) serve as a proof of principle showing the integration of SNP data and phased DNA-methylation information into "hepitypes" and thus the analysis of DNA methylation phylogeny in the somatic evolution of cancer.
|
21750708 |
2011 |
|
Childhood Lymphoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
Data from lymphoma and colorectal cancer samples for SNRPN (imprinted gene), FGF6 (demethylated in the cancer samples) and HS3ST2 (methylated in the cancer samples) serve as a proof of principle showing the integration of SNP data and phased DNA-methylation information into "hepitypes" and thus the analysis of DNA methylation phylogeny in the somatic evolution of cancer.
|
21750708 |
2011 |
|
Malignant neoplasm of prostate
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Examples include the overexpression of FGF2 and FGF6 in prostate cancer, and FGF8 overexpression in breast and prostate cancers.
|
17697126 |
2007 |
|
Prostate carcinoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Examples include the overexpression of FGF2 and FGF6 in prostate cancer, and FGF8 overexpression in breast and prostate cancers.
|
17697126 |
2007 |
|
Medulloblastoma
|
0.010 |
AlteredExpression
|
disease |
LHGDN |
Antitumor activity of fibroblast growth factors (FGFs) for medulloblastoma may correlate with FGF receptor expression and tumor variant.
|
11801566 |
2002 |
|
Carcinoma
|
0.010 |
Biomarker
|
group |
BEFREE |
To determine the T-cell receptor (TCR) V alpha/V beta gene usage of the human autologous gastric tumor-specific cytotoxic T-lymphocytes (CTLs), we first established two pairs of tumor cell lines, HST2 and SSTW, from the malignant peritoneal effusions of signet ring cell carcinomas and their peripheral blood lymphocyte-derived tumor-specific CD8-positive CTL lines, TcHST2 and TcSSTW.
|
8391386 |
1993 |
|
Neoplasms
|
0.010 |
AlteredExpression
|
group |
BEFREE |
The hst-2 cDNA fragment, when inserted into an expression vector, was able to transform NIH3T3 cells effectively, and the resulting transformant formed a well-vascularized tumor in nude mice, thus suggesting an angiogenic property similar to some other members of the family.
|
1549352 |
1992 |