FGFR3, fibroblast growth factor receptor 3, 2261

N. diseases: 654; N. variants: 55
Disease: Carcinoma of lung ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		0.070 Biomarker disease BEFREE Overall, this study provides new insights into the PRMT5/miR-99 family/FGFR3 axis in regulating lung cancer progression and identifies PRMT5 as a promising prognostic biomarker and therapeutic target. 29679612 2018
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		0.070 Biomarker disease BEFREE Our previous studies showed that Fibroblast growth factor receptor 3 (FGFR3) contributed to cell growth in lung cancer. 29850625 2018
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		0.070 GeneticVariation disease BEFREE We identified 4 patients with bladder cancer and 2 patients with lung cancer harboring the FGFR3-BAIAP2L1 fusion through PCR and FISH assay screens. 25589496 2015
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		0.070 GeneticVariation disease BEFREE A novel somatic FGFR3 mutation in primary lung cancer. 24452392 2014
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		0.070 Biomarker disease BEFREE Identification of recurrent FGFR3 fusion genes in lung cancer through kinome-centred RNA sequencing. 23661334 2013
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		0.070 AlteredExpression disease BEFREE Furthermore, miR-99a downregulation is associated with mTOR/FGFR3 upregulation in various human lung cancer cells/tissues. 21383697 2011
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		0.070 Biomarker disease BEFREE Use of an FGFR3 inhibitor (PD173074) obtained similar results with suppression of the autophosphorylation extracellular signal-regulated kinase pathway in HSC-2 cells and lung cancer cell lines. 21577207 2011