Disease: Adult Acute Lymphocytic Leukemia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0751606
Disease: Adult Acute Lymphocytic Leukemia
Adult Acute Lymphocytic Leukemia 		0.040 Biomarker disease BEFREE Analysis of gene expression profiles revealed that the expression of the tumor suppressor gene FHIT is reduced in children with MLL rearranged ALL as compared to ALL patients carrying germ line MLL. 16357833 2006
CUI: C0751606
Disease: Adult Acute Lymphocytic Leukemia
Adult Acute Lymphocytic Leukemia 		0.040 PosttranslationalModification disease BEFREE These results suggest that hypermethylation of the promoter region CpG island of the FHIT gene is a common event and may play an important role in the etiology and pathophysiology of specific cytogenetic subtypes of childhood ALL. 15026336 2004
CUI: C0751606
Disease: Adult Acute Lymphocytic Leukemia
Adult Acute Lymphocytic Leukemia 		0.040 AlteredExpression disease BEFREE We used western blot and solid-phase radioimmunoassay (RIA) to analyze Fhit protein expression in 90 patients with ALL. 11532518 2001
CUI: C0751606
Disease: Adult Acute Lymphocytic Leukemia
Adult Acute Lymphocytic Leukemia 		0.040 AlteredExpression disease BEFREE These findings suggest that the expression of functional FHIT protein was lost in the majority of ALL (76%) and AML (60%) cases. 9823330 1998