RRAS2, RAS related 2, 22800

N. diseases: 48; N. variants: 4
Disease: Breast Carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.030 GeneticVariation disease BEFREE A polymorphism in the TC21 promoter associates with an unfavorable tamoxifen treatment outcome in breast cancer. 19047159 2008
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.030 AlteredExpression disease BEFREE TC21 is a Ras-like GTPase with high oncogenic potential that is found mutated in some human tumors and overexpressed in breast cancer cell lines. 10557073 1999
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.030 GeneticVariation disease BEFREE Thus, we conclude that mutations in TC21 are uncommon in breast carcinomas. 9703274 1998