Malignant neoplasm of breast
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
The objective of this study was to investigate whether the genetic polymorphism rs12665607 of ESR1, rs10995190 of ZNF365, rs3817198 of LSP1 and rs17001868 of SGSM3/MKL1 are associated with the development of breast cancer (BC) in the Chinese women.
|
27432265 |
2017 |
Malignant neoplasm of breast
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
Luciferase assays did not identify SNPs that affect transactivation of ZNF365, but identified a protective haplotype in iCHAV2, associated with silencing of the NRBF2 promoter, implicating this gene in the etiology of breast cancer.
|
26073781 |
2015 |
Malignant neoplasm of breast
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
Associations were also observed with rs10995190 in the ZNF365 gene (P < 1.0 × 10(-6)) and breast cancer risk [HR for the highest vs. lowest quartile, 2.93; 95% confidence interval, 1.73-4.96 and 1.63 (1.10-2.42) for percent and absolute dense volume, respectively].
|
25012995 |
2014 |
Malignant neoplasm of breast
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
We contrast the three methods, CASAM-Area, CASAM-Vol and Volpara directly and in terms of association with breast cancer risk and a known genetic variant for mammographic density and breast cancer, rs10995190 in the gene ZNF365.
|
25329322 |
2014 |
Malignant neoplasm of breast
|
0.500 |
GeneticVariation
|
disease |
GWASDB |
Large-scale genotyping identifies 41 new loci associated with breast cancer risk.
|
23535729 |
2013 |
Malignant neoplasm of breast
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
The ZNF365 locus is associated with breast cancer risk in carriers of mutated BRCA1 and BRCA2, which are important molecules required for DNA damage response.
|
23966166 |
2013 |
Malignant neoplasm of breast
|
0.500 |
GeneticVariation
|
disease |
GWASDB |
Genome-wide association studies identify four ER negative-specific breast cancer risk loci.
|
23535733 |
2013 |
Malignant neoplasm of breast
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
19p13.1 and ZNF365 are susceptibility loci for ovarian cancer and ER subtypes of breast cancer among BRCA1 and BRCA2 mutation carriers.
|
22351618 |
2012 |
Malignant neoplasm of breast
|
0.500 |
Biomarker
|
disease |
BEFREE |
Two of these seven SNPs are in linkage disequilibrium (LD) with SNPs associated with breast cancer (those near ESR1 and PTHLH), and a third (ZNF365) is near, but not in LD with, a breast cancer SNP.
|
22747683 |
2012 |
Malignant neoplasm of breast
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
Common variants at 12p11, 12q24, 9p21, 9q31.2 and in ZNF365 are associated with breast cancer risk for BRCA1 and/or BRCA2 mutation carriers.
|
22348646 |
2012 |
Malignant neoplasm of breast
|
0.500 |
GeneticVariation
|
disease |
GWASDB |
Genome-wide association study identifies breast cancer risk variant at 10q21.2: results from the Asia Breast Cancer Consortium.
|
21908515 |
2011 |
Malignant neoplasm of breast
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
SNP rs10822013 on chromosome 10q21.2, located in the zinc finger protein 365 (ZNF365) gene, showed a consistent association with breast cancer risk in all four stages with a combined per-risk allele odds ratio of 1.10 (95% CI: 1.07-1.14) (P-value for trend = 5.87 × 10(-9)).
|
21908515 |
2011 |
Malignant neoplasm of breast
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
Common variants in ZNF365 have also recently been associated with susceptibility to breast cancer.
|
21278746 |
2011 |
Malignant neoplasm of breast
|
0.500 |
Biomarker
|
disease |
CTD_human |
Common variants in ZNF365 have also recently been associated with susceptibility to breast cancer.
|
21278746 |
2011 |
Malignant neoplasm of breast
|
0.500 |
GeneticVariation
|
disease |
BEFREE |
The chromosome 10 locus was in ZNF365, which contains another variant that has recently been associated with breast cancer in an independent study of unselected cases.
|
21060860 |
2010 |
Malignant neoplasm of breast
|
0.500 |
GeneticVariation
|
disease |
GWASDB |
Genome-wide association study identifies five new breast cancer susceptibility loci.
|
20453838 |
2010 |