KLRK1, killer cell lectin like receptor K1, 22914

N. diseases: 255; N. variants: 2
Disease: Neoplasm Metastasis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis 		0.050 AlteredExpression phenotype BEFREE Their proportion increased, whereas the expression of NKG2D decreased significantly when more than one organ was affected by metastases. 27892653 2017
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis 		0.050 Biomarker phenotype BEFREE NKG2D-mediated immune surveillance is crucial for inhibiting tumor growth and metastases. 28223282 2017
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis 		0.050 Biomarker phenotype BEFREE Thus, NKG2D may have the capacity to drive high malignancy traits underlying metastatic disease. 25291178 2014
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis 		0.050 AlteredExpression phenotype BEFREE Modulation of NKG2D ligand expression and metastasis in tumors by spironolactone via RXRγ activation. 24190430 2013
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis 		0.050 AlteredExpression phenotype BEFREE Thus, HSP70 and inducible NKG2D ligands synergistically promote the activation of mouse NK cells resulting in a reduced tumor growth and suppression of metastatic disease. 17911639 2007