KLRK1, killer cell lectin like receptor K1, 22914

N. diseases: 255; N. variants: 2
Disease: Tumor Immunity ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1519680
Disease: Tumor Immunity
Tumor Immunity 		0.050 Biomarker phenotype BEFREE Impairment of NKG2D-Mediated Tumor Immunity by TGF-β. 31803194 2019
CUI: C1519680
Disease: Tumor Immunity
Tumor Immunity 		0.050 Biomarker phenotype BEFREE The anti-tumor immunity of NKG2D.CAR.NK cells in combination with CD73 targeting was evaluated against multiple solid tumor targets in vitro and humanized mouse xenografts in immunodeficient tumor-bearing mice in vivo. 30514403 2018
CUI: C1519680
Disease: Tumor Immunity
Tumor Immunity 		0.050 Biomarker phenotype BEFREE Release of NKG2DL has been observed in a broad variety of human tumor entities and is thought to interfere with NKG2D-mediated tumor immunity in several ways. 18508446 2008
CUI: C1519680
Disease: Tumor Immunity
Tumor Immunity 		0.050 Biomarker phenotype BEFREE NKG2D ligands in tumor immunity. 18836475 2008
CUI: C1519680
Disease: Tumor Immunity
Tumor Immunity 		0.050 Biomarker phenotype BEFREE Engagement of MIC by the activating immune receptor NKG2D triggers NK cells and augments antigen-specific CTL anti-tumor immunity. 15314693 2004