|
Glomerular Filtration Rate
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
A catalog of genetic loci associated with kidney function from analyses of a million individuals.
|
31152163 |
2019 |
|
Lymphoma, T-Cell, Cutaneous
|
0.010 |
Biomarker
|
disease |
BEFREE |
Among those, we examined the RRP5-homologue and NF-kappa-B-interacting protein PDCD11/ALG-4, which has roles in apoptosis and is a putative driver gene in cutaneous T-cell lymphoma.
|
31056253 |
2019 |
|
Transient Ischemic Attack
|
0.010 |
Biomarker
|
disease |
BEFREE |
Serum PDCD11-Ab level may serve as a potential biomarker for TIA.
|
29507658 |
2018 |
|
Diabetes
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Multivariate logistic regression analysis indicated that the predictive value of PDCD11-Ab levels for TIA [Odds ratio (OR): 2.44, 95% confidence interval (CI): 1.33-4.57, <i>p</i> = 0.0039] was not inferior to other known risk factors for ischemic stroke, including age (OR: 4.97, 95% CI: 2.67-9.48, <i>p</i> < 0.0001); hypertension (OR: 3.21, 95% CI: 1.76-5.86, <i>p</i> = 0.0001); and diabetes (OR: 4.31, 95% CI: 1.74-11.2, <i>p</i> = 0.0015).
|
29507658 |
2018 |
|
Diabetes Mellitus
|
0.010 |
GeneticVariation
|
group |
BEFREE |
Multivariate logistic regression analysis indicated that the predictive value of PDCD11-Ab levels for TIA [Odds ratio (OR): 2.44, 95% confidence interval (CI): 1.33-4.57, <i>p</i> = 0.0039] was not inferior to other known risk factors for ischemic stroke, including age (OR: 4.97, 95% CI: 2.67-9.48, <i>p</i> < 0.0001); hypertension (OR: 3.21, 95% CI: 1.76-5.86, <i>p</i> = 0.0001); and diabetes (OR: 4.31, 95% CI: 1.74-11.2, <i>p</i> = 0.0015).
|
29507658 |
2018 |
|
Hypertensive disease
|
0.010 |
GeneticVariation
|
group |
BEFREE |
Multivariate logistic regression analysis indicated that the predictive value of PDCD11-Ab levels for TIA [Odds ratio (OR): 2.44, 95% confidence interval (CI): 1.33-4.57, <i>p</i> = 0.0039] was not inferior to other known risk factors for ischemic stroke, including age (OR: 4.97, 95% CI: 2.67-9.48, <i>p</i> < 0.0001); hypertension (OR: 3.21, 95% CI: 1.76-5.86, <i>p</i> = 0.0001); and diabetes (OR: 4.31, 95% CI: 1.74-11.2, <i>p</i> = 0.0015).
|
29507658 |
2018 |
|
Cerebrovascular accident
|
0.010 |
Biomarker
|
group |
BEFREE |
Of these, programmed cell death 11 (PDCD11) was determined to be associated with stroke (<i>p</i> < 0.0001), as evidenced from the second screening using AlphaLISA.
|
29507658 |
2018 |
|
Transient Cerebral Ischemia
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Elevation of autoantibody level against PDCD11 in patients with transient ischemic attack.
|
29507658 |
2018 |
|
Schizophrenia
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Our data do not support the role of rare PDCD11 variations in conferring substantial risk for schizophrenia in the Japanese population.
|
28657695 |
2017 |