Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0024117
Disease: Chronic Obstructive Airway Disease
Chronic Obstructive Airway Disease 		0.200 Biomarker disease RGD In COPD rats model, miR-3202 was reduced while FAIM2 was up-regulated accordingly. 29208459 2018
CUI: C0028754
Disease: Obesity
Obesity 		0.190 GeneticVariation disease BEFREE Differential gene expression between islets from normoglycemic and hyperglycemic patients was prominent for the glycolytic enzyme ALDOB and the obesity-associated gene FAIM2. 30202879 2018
CUI: C0028754
Disease: Obesity
Obesity 		0.190 PosttranslationalModification disease BEFREE This study provides the first evidence that the methylation levels of the FAIM2 promoter are significantly associated with obesity and are independently associated with dyslipidaemia and its components in Chinese children. 25696115 2015
CUI: C0028754
Disease: Obesity
Obesity 		0.190 Biomarker disease BEFREE Whether the molecular mechanisms by which FAIM2 affects obesity are involved in lifestyle is unclear. 25922107 2015
CUI: C0028754
Disease: Obesity
Obesity 		0.190 GeneticVariation disease BEFREE In the meta-analysis of 42 studies for 11 obesity/BMI-associated loci, we observed a statistically significant association of the FTO rs9939609 polymorphism (66 425 T2D cases/239 689 normoglycaemic subjects; P = 1·00 × 10(-41) ) and six other variants with T2D risk (17 915 T2D cases/27 531 normoglycaemic individuals: n = 40 629-130 001; all P < 0·001 for SH2B1 rs7498665, FAIM2 rs7138803, TMEM18 rs7561317, GNPDA2 rs10938397, BDNF rs925946 and NEGR1 rs2568958). 24528214 2014
CUI: C0028754
Disease: Obesity
Obesity 		0.190 GeneticVariation disease BEFREE We replicated the association between the FAIM2-rs7138803 polymorphism and greater obesity risk (OR: 1.08; 95% CI: 1.01-1.16; P = 0.011; per-A allele). 24393375 2014
CUI: C0028754
Disease: Obesity
Obesity 		0.190 Biomarker disease BEFREE This study highlighted the importance of above two candidate genes (SH2B1 and FAIM2) in the risk of overweight/obesity. 24621099 2014
CUI: C0028754
Disease: Obesity
Obesity 		0.190 GeneticVariation disease BEFREE Common rs7138803 variant of FAIM2 and obesity in Han Chinese. 23924573 2013
CUI: C0028754
Disease: Obesity
Obesity 		0.190 GeneticVariation disease BEFREE Eight loci, rs10968576 (BDNF), rs3817334 (MTCH2), rs1558902 (FTO), rs571312 (MC4R), rs543874 (SEC16B), rs987237 (TFAP2B), rs2867125 (TMEM18) and rs7138803 (FAIM2), were previously known obesity susceptibility loci, and the remaining four loci, rs1514175 (TNNI3K), rs206936 (NUDT3), rs4771122 (MTIF3) and rs2241423 (MAP2K5), were newly identified as BMI loci by the GIANT study. 22041983 2012
CUI: C0028754
Disease: Obesity
Obesity 		0.190 GeneticVariation disease GWASDB Genome-wide population-based association study of extremely overweight young adults--the GOYA study. 21935397 2011
CUI: C0028754
Disease: Obesity
Obesity 		0.190 Biomarker disease BEFREE SNPs in GNPDA2, BDNF, FAIM2 and MC4R genes were marginally associated with obesity (P<0.05). 19851340 2009
CUI: C0005845
Disease: Blood urea nitrogen measurement
Blood urea nitrogen measurement 		0.100 GeneticVariation phenotype GWASCAT A catalog of genetic loci associated with kidney function from analyses of a million individuals. 31152163 2019
CUI: C0202239
Disease: Uric acid measurement (procedure)
Uric acid measurement (procedure) 		0.100 GeneticVariation phenotype GWASCAT Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels. 31578528 2019
CUI: C0424678
Disease: Lean body mass
Lean body mass 		0.100 GeneticVariation phenotype GWASCAT Genomics of body fat percentage may contribute to sex bias in anorexia nervosa. 30593698 2019
CUI: C1305855
Disease: Body mass index
Body mass index 		0.100 GeneticVariation phenotype GWASCAT Genotype-by-environment interactions inferred from genetic effects on phenotypic variability in the UK Biobank. 31453325 2019
CUI: C1305855
Disease: Body mass index
Body mass index 		0.100 GeneticVariation phenotype GWASCAT Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry. 30239722 2019
CUI: C1305855
Disease: Body mass index
Body mass index 		0.100 GeneticVariation phenotype GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
CUI: C0005910
Disease: Body Weight
Body Weight 		0.100 GeneticVariation phenotype GWASCAT Whole-Genome Sequencing Coupled to Imputation Discovers Genetic Signals for Anthropometric Traits. 28552196 2017
CUI: C0455829
Disease: Waist Circumference
Waist Circumference 		0.100 GeneticVariation phenotype GWASCAT Whole-Genome Sequencing Coupled to Imputation Discovers Genetic Signals for Anthropometric Traits. 28552196 2017
CUI: C0562350
Disease: Hip circumference
Hip circumference 		0.100 GeneticVariation phenotype GWASCAT Whole-Genome Sequencing Coupled to Imputation Discovers Genetic Signals for Anthropometric Traits. 28552196 2017
CUI: C1305855
Disease: Body mass index
Body mass index 		0.100 GeneticVariation phenotype GWASCAT Genome-wide association study identifies 112 new loci for body mass index in the Japanese population. 28892062 2017
CUI: C1305855
Disease: Body mass index
Body mass index 		0.100 GeneticVariation phenotype GWASCAT Whole-Genome Sequencing Coupled to Imputation Discovers Genetic Signals for Anthropometric Traits. 28552196 2017
CUI: C0425782
Disease: Breast size
Breast size 		0.100 GeneticVariation phenotype GWASCAT Detection and interpretation of shared genetic influences on 42 human traits. 27182965 2016
CUI: C1305855
Disease: Body mass index
Body mass index 		0.100 GeneticVariation phenotype GWASCAT Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index. 26604143 2016
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia 		0.020 Biomarker disease BEFREE The role of GRINA in transient brain ischemia, its potential synergistic effects with FAIM2 and its regulation by EPO treatment were assessed. 31211943 2019