FOXC2, forkhead box C2, 2303

N. diseases: 168; N. variants: 18
Disease: Ischemia of kidney ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0920646
Disease: Ischemia of kidney
Ischemia of kidney 		0.010 Biomarker disease BEFREE In this study, we show that both mRNA and protein levels of Foxc2 increase 1 day after kidney ischemia/reperfusion in sublethally injured tubular cells and that the protein is located in the cytoplasm rather than the nucleus of these cells. in vitro studies of cultured tubular cells confirm the cytoplasmic location of Foxc2 and show that increased cytoplasmic expression of Foxc2 correlates with epithelial differentiation rather than dedifferentiation. 19935708 2010