FOXO1, forkhead box O1, 2308

N. diseases: 380; N. variants: 16
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.350 Biomarker group CTD_human Sequencing of prostate cancers identifies new cancer genes, routes of progression and drug targets. 29662167 2018
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.350 Biomarker group LHGDN Forkhead protein FKHR and its phosphorylated form p-FKHR in human prostate cancer. 17597184 2007
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.350 AlteredExpression group LHGDN FOXO1A is a candidate for the 13q14 tumor suppressor gene inhibiting androgen receptor signaling in prostate cancer. 16849544 2006
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.350 AlteredExpression group LHGDN Suppression of FOXO1 activity by FHL2 through SIRT1-mediated deacetylation. 15692560 2005
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.350 AlteredExpression group LHGDN Androgens negatively regulate forkhead transcription factor FKHR (FOXO1) through a proteolytic mechanism in prostate cancer cells. 14726521 2004
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms
0.350 Biomarker group LHGDN AKT-independent protection of prostate cancer cells from apoptosis mediated through complex formation between the androgen receptor and FKHR. 12482965 2003