FOXO3, forkhead box O3, 2309

N. diseases: 381; N. variants: 30
Disease: Left Ventricular Hypertrophy ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0149721
Disease: Left Ventricular Hypertrophy
Left Ventricular Hypertrophy 		0.220 Biomarker disease BEFREE The protein kinase B (AKT)/FOXO3 and AKT/mammalian target of rapamycin (mTOR) pathways are also proposed regulators of LVH induced by pressure-overload. 30718600 2019
CUI: C0149721
Disease: Left Ventricular Hypertrophy
Left Ventricular Hypertrophy 		0.220 Biomarker disease BEFREE However, miR-212 seems to play a role in the development of LVH via FOXO3-independent mechanisms in RIHD. 31380269 2019
CUI: C0149721
Disease: Left Ventricular Hypertrophy
Left Ventricular Hypertrophy 		0.220 Biomarker disease RGD Forkhead class O transcription factor 3a activation and Sirtuin1 overexpression in the hypertrophied myocardium of the diabetic Goto-Kakizaki rat. 18192848 2008