FLNA, filamin A, 2316

N. diseases: 571; N. variants: 85
Disease: Malignant neoplasm of breast ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		0.380 AlteredExpression disease BEFREE These results suggest that BRCA1 expression could be regulated by FlnA in the breast cancer cell line, MCF-7. 30405761 2018
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		0.380 AlteredExpression disease BEFREE Moreover, aberrant expression of FLNa has been observed in many cancers, such as parathyroid tumor, cervical cancer, and breast cancer. 29272322 2018
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		0.380 Biomarker disease BEFREE The present study aimed to examine the interaction of filamin A with 14-3-3-σ in the invasion and migration of breast cancer. 30074213 2018
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		0.380 Biomarker disease CTD_human Genomic landscapes of breast fibroepithelial tumors. 26437033 2015
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		0.380 AlteredExpression disease BEFREE Using MDA-MB-231 as a model breast cancer cell line, we provide evidence that PFN1 overexpression is associated with alterations in the expression of proteins that have been functionally linked to cell proliferation (FKPB1A, HDGF, MIF, PRDX1, TXNRD1, LGALS1, STMN1, LASP1, S100A11, S100A6), survival (HSPE1, HSPB1, HSPD1, HSPA5 and PPIA, YWHAZ, CFL1, NME1) and motility (CFL1, CORO1B, PFN2, PLS3, FLNA, FLNB, NME2, ARHGDIB). 25454514 2014
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		0.380 Biomarker disease BEFREE Furthermore, in breast cancers loss of filamin A has been correlated with increased metastatic potential. 22595522 2012
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		0.380 Biomarker disease BEFREE Filamin A regulates focal adhesion disassembly and suppresses breast cancer cell migration and invasion. 20937704 2010
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		0.380 AlteredExpression disease BEFREE We used three pairs of cell lines with normal and reduced filamin-A expression, including breast cancer and melanoma cells. 19808958 2009
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		0.380 Biomarker disease BEFREE Breast cancer and the MNSs blood groups. 2582715 1990