MLC1, modulator of VRAC current 1, 23209

N. diseases: 87; N. variants: 45
Disease: Schizophrenia, Catatonic ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0036344
Disease: Schizophrenia, Catatonic
Schizophrenia, Catatonic 		0.340 Biomarker disease PSYGENET MLC1 gene is associated with schizophrenia and bipolar disorder in Southern India. 15992519 2005
CUI: C0036344
Disease: Schizophrenia, Catatonic
Schizophrenia, Catatonic 		0.340 GeneticVariation disease BEFREE A missense mutation in MLC1 (putative cation-channel gene on 22q13) co-segregating with periodic catatonic schizophrenia has been reported. 15992519 2005
CUI: C0036344
Disease: Schizophrenia, Catatonic
Schizophrenia, Catatonic 		0.340 Biomarker disease BEFREE Our results argue against the involvement of WKL1 in SCZ susceptibility. 14755440 2004
CUI: C0036344
Disease: Schizophrenia, Catatonic
Schizophrenia, Catatonic 		0.340 Biomarker disease PSYGENET Is the WKL1 gene associated with schizophrenia? 14755440 2004
CUI: C0036344
Disease: Schizophrenia, Catatonic
Schizophrenia, Catatonic 		0.340 Biomarker disease PSYGENET The brain-specific protein MLC1 implicated in megalencephalic leukoencephalopathy with subcortical cysts is expressed in glial cells in the murine brain. 14603469 2003
CUI: C0036344
Disease: Schizophrenia, Catatonic
Schizophrenia, Catatonic 		0.340 GeneticVariation disease BEFREE The role, suggested by others, of a mutation in the MLC1gene in catatonic schizophrenia and the possible function of the MLC1 protein as a cation channel are discussed. 11935341 2002
CUI: C0036344
Disease: Schizophrenia, Catatonic
Schizophrenia, Catatonic 		0.340 Biomarker disease PSYGENET A novel polymorphism in exon 11 of the WKL1 gene, shows no association with schizophrenia. 12111645 2002
CUI: C0036344
Disease: Schizophrenia, Catatonic
Schizophrenia, Catatonic 		0.340 GeneticVariation disease BEFREE A missense mutation in exon 11 of the WKL1 gene on chromosome 22 was found to be associated with cases of catatonic schizophrenia in a single large pedigree. 12111645 2002