MLC1, modulator of VRAC current 1, 23209

N. diseases: 87; N. variants: 45
Disease: Severe Aplastic Anemia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1883018
Disease: Severe Aplastic Anemia
Severe Aplastic Anemia 		0.020 Biomarker disease BEFREE In this report, we describe a patient with severe aplastic anemia who developed a malignant B cell lymphoplasmacytoid proliferation 48 days after undergoing allogeneic marrow transplantation from her HLA-matched MLC-nonreactive brother. 2820089 1987
CUI: C1883018
Disease: Severe Aplastic Anemia
Severe Aplastic Anemia 		0.020 Biomarker disease BEFREE In vitro hemopoietic culture studies of marrow from the patient's HLA-MLC-matched siblings showed normal numbers of pluripotential and committed hemopoietic progenitors; in vitro hemopoietic colony formation from the patient was markedly subnormal, consistent with the clinical picture of severe aplastic anemia. 3518419 1986