SULF1, sulfatase 1, 23213

N. diseases: 83; N. variants: 3
Disease: Liver neoplasms ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms 		0.020 Biomarker group BEFREE Although a small fraction of liver tumours and some liver tumour cell lines can grow in the absence of Sulf1 and/or Sulf2, the in vitro overexpression of these genes further confirms their growth-promoting effect while transient reduction in their levels by neutralisation antibodies reduces growth. 27013228 2016
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms 		0.020 Biomarker group BEFREE The heparin-degrading endosulfatase SULF1 functions as a liver tumor suppressor. 19376607 2009