SIK2, salt inducible kinase 2, 23235

N. diseases: 38; N. variants: 7
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
0.030 Biomarker disease BEFREE However, the role of SIK2 in glucose metabolism reprogramming remains unclear in ovarian cancer (OC) cells. 31639424 2020
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
0.030 Biomarker disease BEFREE These findings identify SIK2 at the apex of the adipocyte-induced signaling cascades in cancer cells and make a compelling case for targeting SIK2 for therapy in ovarian cancer. 27478041 2016
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
0.030 Biomarker disease BEFREE SIK2 is a centrosome kinase required for bipolar mitotic spindle formation that provides a potential target for therapy in ovarian cancer. 20708153 2010