SIK2, salt inducible kinase 2, 23235

N. diseases: 38; N. variants: 7
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1140680
Disease: Malignant neoplasm of ovary
Malignant neoplasm of ovary
0.030 Biomarker disease BEFREE However, the role of SIK2 in glucose metabolism reprogramming remains unclear in ovarian cancer (OC) cells. 31639424 2020
CUI: C1140680
Disease: Malignant neoplasm of ovary
Malignant neoplasm of ovary
0.030 Biomarker disease BEFREE These findings identify SIK2 at the apex of the adipocyte-induced signaling cascades in cancer cells and make a compelling case for targeting SIK2 for therapy in ovarian cancer. 27478041 2016
CUI: C1140680
Disease: Malignant neoplasm of ovary
Malignant neoplasm of ovary
0.030 Biomarker disease BEFREE We believe these data identify SIK2 as a plausible target for therapy in ovarian cancers. 20708153 2010