Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
0.330 Biomarker disease BEFREE In this study, a two-stage case-control study of 1471 Han Chinese was conducted to investigate the genetic association between the Arc gene and AD. 28108859 2018
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
0.330 GeneticVariation disease BEFREE In this study, we investigated genetic variation in human ARC and the risk of developing AD. 22622366 2012
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
0.330 Biomarker disease CTD_human Finally, we showed that Arc levels are decreased in the cortex of AD brains. 18503570 2009
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
0.330 Biomarker disease BEFREE In addition, levels of mRNAs encoding proteins not previously implicated in AD were reduced in CA1 tangle-bearing neurons, suggesting that these proteins (eg, activity-regulated cytoskeleton-associated protein, focal adhesion kinase, glutaredoxin, utrophin) may be novel mediators of NFT formation or degeneration in affected neurons. 10894219 2000