|
Osteosarcoma
|
0.020 |
Biomarker
|
disease |
BEFREE |
Cisplatin-sensitive human osteosarcoma OST cells and acquired cisplatin-resistant OST/R cells derived from OST cells were used.
|
10697522 |
2000 |
|
Osteosarcoma of bone
|
0.020 |
Biomarker
|
disease |
BEFREE |
Cisplatin-sensitive human osteosarcoma OST cells and acquired cisplatin-resistant OST/R cells derived from OST cells were used.
|
10697522 |
2000 |
|
Childhood Osteosarcoma
|
0.020 |
Biomarker
|
disease |
BEFREE |
Cisplatin-sensitive human osteosarcoma OST cells and acquired cisplatin-resistant OST/R cells derived from OST cells were used.
|
10697522 |
2000 |
|
Tremor
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
Bilateral subthalamic nucleus DBS holds the most promising results for patients with tremor, severe motor fluctuations and dyskinesias from L-dopa, with the best improvements seen in daily activities and quality of life.
|
12869808 |
2003 |
|
Dyskinetic syndrome
|
0.080 |
Biomarker
|
disease |
BEFREE |
Bilateral subthalamic nucleus DBS holds the most promising results for patients with tremor, severe motor fluctuations and dyskinesias from L-dopa, with the best improvements seen in daily activities and quality of life.
|
12869808 |
2003 |
|
Blood spots
|
0.060 |
Biomarker
|
disease |
BEFREE |
Detection of viral DNA in dried blood spots using the Guthrie card (DBS test) is a reliable and practical method of diagnosing congenital cytomegalovirus (CMV) infection.
|
15135749 |
2004 |
|
Congenital cytomegalovirus infection
|
0.020 |
GeneticVariation
|
disease |
BEFREE |
We tested DBS from: (A) 39 laboratory reference cases; (B) 156 neonates suspected of having congenital CMV infection; (C) 119 children examined for the retrospective diagnosis of congenital CMV; (D) mock specimens prepared with known amounts of viral DNA.
|
15135749 |
2004 |
|
Cytomegalovirus Infections
|
0.010 |
Biomarker
|
group |
BEFREE |
Detection of viral DNA in dried blood spots using the Guthrie card (DBS test) is a reliable and practical method of diagnosing congenital cytomegalovirus (CMV) infection.
|
15135749 |
2004 |
|
Osteosarcoma
|
0.020 |
AlteredExpression
|
disease |
BEFREE |
In the present study, we examined telomerase activity in clinical samples from osteosarcoma and soft tissue sarcoma and representative sarcoma cell lines (HOS, OST and Saos2), using the telomeric repeat amplification protocol (TRAP) assay.
|
15138570 |
2004 |
|
Osteosarcoma of bone
|
0.020 |
AlteredExpression
|
disease |
BEFREE |
In the present study, we examined telomerase activity in clinical samples from osteosarcoma and soft tissue sarcoma and representative sarcoma cell lines (HOS, OST and Saos2), using the telomeric repeat amplification protocol (TRAP) assay.
|
15138570 |
2004 |
|
Childhood Osteosarcoma
|
0.020 |
AlteredExpression
|
disease |
BEFREE |
In the present study, we examined telomerase activity in clinical samples from osteosarcoma and soft tissue sarcoma and representative sarcoma cell lines (HOS, OST and Saos2), using the telomeric repeat amplification protocol (TRAP) assay.
|
15138570 |
2004 |
|
Dystonia
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
This study shows the benefits of pallidal DBS for the dystonia of PKAN patients.
|
15852393 |
2005 |
|
Dystonia Disorders
|
0.100 |
Biomarker
|
group |
BEFREE |
This study shows the benefits of pallidal DBS for the dystonia of PKAN patients.
|
15852393 |
2005 |
|
Hallervorden-Spatz Syndrome
|
0.030 |
Biomarker
|
disease |
BEFREE |
This study shows the benefits of pallidal DBS for the dystonia of PKAN patients.
|
15852393 |
2005 |
|
Blood spots
|
0.060 |
Biomarker
|
disease |
BEFREE |
A test based on viral DNA extraction from neonatal dried blood spots on Guthrie cards and its amplification by means of a nested PCR (DBS test) seems to offer the best characteristics for use in screening.
|
16384745 |
2006 |
|
Donnai-Barrow syndrome
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Donnai-Barrow syndrome (DBS/FOAR) in a child with a homozygous LRP2 mutation due to complete chromosome 2 paternal isodisomy.
|
18553518 |
2008 |
|
Renal Cell Carcinoma
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Results from this study provide evidence that individuals with a higher number of genetic variations in the DBS repair pathway are at an increased risk for renal cell carcinoma.
|
18768505 |
2008 |
|
Conventional (Clear Cell) Renal Cell Carcinoma
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Results from this study provide evidence that individuals with a higher number of genetic variations in the DBS repair pathway are at an increased risk for renal cell carcinoma.
|
18768505 |
2008 |
|
Congenital infectious disease
|
0.010 |
Biomarker
|
group |
BEFREE |
To assess the rate of HHV-6 vertical transmission in comparison to CMV, we analyzed cord blood spots dried on cards (Dried Blood Spots, DBS) collected during a multi-center study on HIV congenital infections in Italy.
|
18855654 |
2008 |
|
Blood spots
|
0.060 |
Biomarker
|
disease |
BEFREE |
Moreover, we investigated whether dried plasma and blood spots (DPS and DBS, respectively) give comparable viral load (VL) results.
|
19193835 |
2009 |
|
Immunologic Deficiency Syndromes
|
0.010 |
Biomarker
|
group |
BEFREE |
DBS could be used as an alternative for DPS depending on HIV RNA cutoffs for virological failure.
|
19193835 |
2009 |
|
Malignant neoplasm of breast
|
0.010 |
Biomarker
|
disease |
BEFREE |
The rho-specific guanine nucleotide exchange factor Dbs regulates breast cancer cell migration.
|
19366686 |
2009 |
|
Breast Carcinoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
The rho-specific guanine nucleotide exchange factor Dbs regulates breast cancer cell migration.
|
19366686 |
2009 |
|
Blood spots
|
0.060 |
AlteredExpression
|
disease |
BEFREE |
Dried spots on filter paper made of whole blood (dried blood spots; DBS), plasma (dried plasma spots; DPS) or serum (dried serum spots) hold promise as an affordable and practical alternative specimen source to liquid plasma for HIV type-1 (HIV-1) viral load determination and drug resistance genotyping in the context of the rapidly expanding access to antiretroviral therapy (ART) for HIV-1-infected individuals in low- and middle-income countries.
|
19704164 |
2009 |
|
Dystonia
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
The present study confirms the effectiveness of pallidal DBS in a new family with hereditary primary segmental and generalized dystonia.
|
19890997 |
2009 |