POFUT2, protein O-fucosyltransferase 2, 23275

N. diseases: 6; N. variants: 0
Disease: Malaria ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0024530
Disease: Malaria
Malaria 		0.010 Biomarker disease BEFREE Therefore, POFUT2 plays a similar role in malaria parasites to that in metazoans: it ensures the trafficking of Plasmodium TSR proteins as part of a non-canonical glycosylation-dependent endoplasmic reticulum protein quality control mechanism.The role of O-glycosylation in the malaria life cycle is largely unknown. 28916755 2017