WWC1, WW and C2 domain containing 1, 23286

N. diseases: 71; N. variants: 13
Disease: Amnesia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0002622
Disease: Amnesia
Amnesia 		0.010 Biomarker disease BEFREE Here we report abnormal acetylation of K274 and K281 on tau, identified in AD brains, promotes memory loss and disrupts synaptic plasticity by reducing postsynaptic KIdney/BRAin (KIBRA) protein, a memory-associated protein. 27041503 2016