Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.530 PosttranslationalModification disease BEFREE The sensitivity of NDRG4, GATA5, FOXE1, and SYNE1 methylation in all stages of colorectal cancer (154 cases, 444 controls) was 27% [95% confidence interval (CI), 20%-34%), 18% (95% CI, 12%-24%), 46% (95% CI, 38%-54%), and 47% (95% CI, 39%-55%), with a specificity of 95% (95% CI, 93%-97%), 99% (95% CI, 98%-100%), 93% (95% CI, 91%-95%), and 96% (95% CI, 94%-98%), respectively. 25538088 2015
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.530 GeneticVariation disease BEFREE Three genes (ADAMTS4, CYTL1, and SYNE1) harbored rare loss-of-function variants in both early-onset and familial CRC cases. 25749350 2015
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.530 Biomarker disease BEFREE Neither occurred in controls, whereas promotor hypermethylation was detected in biopsies of 60% of patients with colitis-associated colorectal cancer for FOXE1 and 80% for SYNE1. 24280874 2014
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.530 Biomarker disease CTD_human Genomic and epigenomic integration identifies a prognostic signature in colon cancer. 21278247 2011
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.530 Biomarker disease CTD_human Convergence of mutation and epigenetic alterations identifies common genes in cancer that predict for poor prognosis. 18507500 2008
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.530 GeneticVariation disease UNIPROT