FN1, fibronectin 1, 2335

N. diseases: 724; N. variants: 33
Disease: Apert syndrome ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0001193
Disease: Apert syndrome
Apert syndrome 		0.020 AlteredExpression disease BEFREE Elevated synthesis of fibronectin in the calvaria of patients with Apert syndrome and increased fibronectin gene expression in port wine-derived fibroblasts of patients with Sturge-Weber disease have also been reported. 29476210 2018
CUI: C0001193
Disease: Apert syndrome
Apert syndrome 		0.020 Biomarker disease BEFREE The phenotype of cultured fibroblasts from patients affected by Apert's syndrome, a rare connective disorder, differs from that of normal cells in its extracellular matrix macromolecule composition (glycosaminoglycans, collagens and fibronectin) and is further modulated by treatment with interleukins (ILs). 9628325 1998