FN1, fibronectin 1, 2335

N. diseases: 724; N. variants: 33
Disease: Morphologically altered structure ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1260954
Disease: Morphologically altered structure
Morphologically altered structure 		0.020 Biomarker disease BEFREE TNIIIA2 also strongly promoted glioblastoma multiforme cell migration, which was accompanied by an epithelial-mesenchymal transition-like morphologic change on the fibronectin substrate. 31189613 2019
CUI: C1260954
Disease: Morphologically altered structure
Morphologically altered structure 		0.020 AlteredExpression disease BEFREE Here, we show that overexpression of a constitutively active JNK in human breast cancer cells did not cause apoptosis, but actually induced cell migration and invasion, a morphologic change associated with epithelial-mesenchymal transition (EMT), expression of mesenchymal-specific markers vimentin and fibronectin, and activity of activator protein transcription factors. 20145041 2010