Disease: Primary malignant neoplasm ×
Source: BEFREE ×
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm 		0.030 GeneticVariation group BEFREE Such a general role of ChAHP in governing cell fate plasticity may explain why ADNP mutations affect several organs and body functions and contribute to cancer progression<sup>1,3,4</sup>. 29795351 2018
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm 		0.030 Biomarker group BEFREE In human patients with colon cancer, high ADNP expression was linked to good prognosis.<b>Conclusions:</b> Our findings indicate that ADNP is a tumor suppressor and promising prognostic marker, and that ketamine treatment with ADNP induction is a potential therapeutic approach that may add benefit to current treatment protocols for patients with colorectal cancer.<i>Clin Cancer Res; 23(11); 2769-80.©2016 AACR</i>. 27903678 2017
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm 		0.030 GeneticVariation group BEFREE ADNP is discovered here as unique to chordata with specific autism mutations different from cancer-associated mutation. 25428252 2015