SIRT5, sirtuin 5, 23408

N. diseases: 63; N. variants: 2
Disease: Hyperglycemia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0020456
Disease: Hyperglycemia
Hyperglycemia 		0.010 Biomarker disease BEFREE However, mice lacking both SIRT3 and SIRT5 (Sirt3<sup>-/-</sup>Sirt5<sup>-/-</sup> mice) exhibited significant evidence of inner retinal dysfunction after induction of hyperglycemia compared to hyperglycemic littermate controls, although this dysfunction was not accompanied by gross morphological changes in the retina. 30846716 2019