SIRT3, sirtuin 3, 23410

N. diseases: 227; N. variants: 11
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.320 AlteredExpression disease BEFREE We identified that miR-31 directly targeted SIRT3 in OSCC cells, and a reverse correlation between miR-31 expression and SIRT3 expression was noted in OSCC tumors. 31055111 2019
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.320 AlteredExpression disease BEFREE NSCLC tissue of squamous cell carcinoma type had higher SIRT3 expression compared with other types (P<0.05). 28197634 2017
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma
0.320 Biomarker disease CTD_human To further assess the in vivo role of SIRT3 in OSCC carcinogenesis, a floor-of-mouth oral cancer murine model was used to study the effect of SIRT3 down-regulation on OSCC tumor growth in immunodeficient mice. 21472714 2011