SIRT3, sirtuin 3, 23410

N. diseases: 227; N. variants: 11
Disease: Ischemic stroke ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0948008
Disease: Ischemic stroke
Ischemic stroke 		0.040 Biomarker disease BEFREE Taken together, this research not only demonstrated PPAR-γ might benefit to the growth of endothelial cell though activating Sirt3 but also indicated its potential value in the treatment for ischemic stroke. 31729962 2019
CUI: C0948008
Disease: Ischemic stroke
Ischemic stroke 		0.040 Biomarker disease BEFREE Sirt3 deficiency impairs neurovascular recovery in ischemic stroke. 29777578 2018
CUI: C0948008
Disease: Ischemic stroke
Ischemic stroke 		0.040 Biomarker disease BEFREE In summary, these findings demonstrate that the Sirt1-Sirt3 axis might act as an important modulator in BBB physiology, and could be a therapeutic target for ischemic stroke via regulating mitochondrial ROS generation. 28965081 2018
CUI: C0948008
Disease: Ischemic stroke
Ischemic stroke 		0.040 Biomarker disease BEFREE Sirt3 Mediates the Inhibitory Effect of Adjudin on Astrocyte Activation and Glial Scar Formation following Ischemic Stroke. 29311941 2017