SIRT1, sirtuin 1, 23411

N. diseases: 675; N. variants: 21
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0744474
Disease: Gram-positive bacteremia
Gram-positive bacteremia
0.010 AlteredExpression disease BEFREE Myeloid SIRT1 expression does not change mortality in gram-negative toxin-induced shock or gram-positive bacteremia, suggesting that therapeutic suppression of SIRT1 may be done safely without suppression of myeloid cell-specific immune responses to severe bacterial infections. 24386389 2013