SIRT1, sirtuin 1, 23411

N. diseases: 675; N. variants: 21
Disease: female puberty ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0848255
Disease: female puberty
female puberty 		0.010 Biomarker phenotype BEFREE Here, we identify Sirtuin 1 (SIRT1), a fuel-sensing deacetylase, as a molecule that restrains female puberty via epigenetic repression of the puberty-activating gene, Kiss1. 30305620 2018