SIRT1, sirtuin 1, 23411

N. diseases: 675; N. variants: 21
Disease: Cholesterol gallstones ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0856727
Disease: Cholesterol gallstones
Cholesterol gallstones 		0.010 GeneticVariation disease BEFREE Furthermore, we show that hepatocyte-specific deletion of SIRT1 leads to derangements in bile acid metabolism, predisposing the mice to development of cholesterol gallstones on a lithogenic diet. 22290433 2012