NCS1, neuronal calcium sensor 1, 23413

N. diseases: 48; N. variants: 2
Disease: Malignant neoplasm of liver ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0345904
Disease: Malignant neoplasm of liver
Malignant neoplasm of liver 		0.010 AlteredExpression disease BEFREE This protein is potentially useful because increased NCS1 regulates Ca2<sup>+</sup> signaling and increased Ca2<sup>+</sup> signaling is a hallmark of metastatic cancers, conferring cellular motility and an increasingly aggressive phenotype to tumors.<b>Methods:</b> We explored the relationship between NCS1 expression levels and patient survival in two publicly available liver cancer cohorts and a tumor microarray using data mining strategies.<b>Results:</b> High NCS1 expression levels are significantly associated with worse disease outcome in Asian patients within these cohorts. 29789326 2018