TPSD1, tryptase delta 1, 23430

N. diseases: 27; N. variants: 1
Disease: Hyperalgesia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0020429
Disease: Hyperalgesia
Hyperalgesia 		0.010 Biomarker phenotype BEFREE Inflammatory proteases (mast cell tryptase and trypsins) cleave protease-activated receptor 2 (PAR2) on spinal afferent neurons and cause persistent inflammation and hyperalgesia by unknown mechanisms. 15128844 2004