BRD4, bromodomain containing 4, 23476

N. diseases: 335; N. variants: 6
Disease: Glioblastoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0017636
Disease: Glioblastoma
Glioblastoma 		0.320 Biomarker disease BEFREE The direct and indirect effects of µCAP on glioblastoma (U87MG-RedFluc) cancer cells were investigated in vitro<i>.</i> The results indicate that µCAP generates short- and long-lived species and radicals (i.e., hydroxyl radical (OH), hydrogen peroxide (H₂O₂), and nitrite (NO₂<sup>-</sup>), etc.) with increasing tumor cell death in a dose-dependent manner. 28555065 2017
CUI: C0017636
Disease: Glioblastoma
Glioblastoma 		0.320 Biomarker disease CTD_human OTX015 (MK-8628), a novel BET inhibitor, displays in vitro and in vivo antitumor effects alone and in combination with conventional therapies in glioblastoma models. 27388964 2016
CUI: C0017636
Disease: Glioblastoma
Glioblastoma 		0.320 Biomarker disease CTD_human EGFR Mutation Promotes Glioblastoma through Epigenome and Transcription Factor Network Remodeling. 26455392 2015
CUI: C0017636
Disease: Glioblastoma
Glioblastoma 		0.320 AlteredExpression disease BEFREE Disruption of BRD4 expression in glioblastoma cells reduced cell cycle progression. 24496381 2014