FOLR2, folate receptor beta, 2350

N. diseases: 105; N. variants: 4
Disease: Solid Neoplasm ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0280100
Disease: Solid Neoplasm
Solid Neoplasm 		0.030 AlteredExpression phenotype BEFREE Recently, the folate receptor alpha has emerged as an attractive theranostic target due to its overexpression in multiple solid tumors and its great functional versatility. 31761235 2020
CUI: C0280100
Disease: Solid Neoplasm
Solid Neoplasm 		0.030 Biomarker phenotype BEFREE Phase 1 dose-escalation study of mirvetuximab soravtansine (IMGN853), a folate receptor α-targeting antibody-drug conjugate, in patients with solid tumors. 28440955 2017
CUI: C0280100
Disease: Solid Neoplasm
Solid Neoplasm 		0.030 AlteredExpression phenotype BEFREE FR-β is known to be expressed on several hematologic malignancies and on activated macrophages, but little is known about FR-β expression in solid tumors. 26248049 2015