Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms 		0.310 AlteredExpression group BEFREE Here, we investigated the transcriptional regulation of HA-1 gene expression in cancer. 19096014 2009
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms 		0.310 Biomarker group CTD_human Moreover, we detected HA-1 promoter hypermethylation in primary cancers. 19096014 2009
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.310 Biomarker group CTD_human Our data suggest that promoter hypermethylation contributes to the HA-1 gene regulation in tumors. 19096014 2009
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.310 Biomarker group BEFREE Our data suggest that promoter hypermethylation contributes to the HA-1 gene regulation in tumors. 19096014 2009
CUI: C0032914
Disease: Pre-Eclampsia
Pre-Eclampsia 		0.300 Biomarker phenotype CTD_human Trophoblast expression of the minor histocompatibility antigen HA-1 is regulated by oxygen and is increased in placentas from preeclamptic women. 26095815 2015
CUI: C0086692
Disease: Benign Neoplasm
Benign Neoplasm 		0.300 Biomarker group CTD_human Hypomethylating drugs convert HA-1-negative solid tumors into targets for stem cell-based immunotherapy. 19096014 2009
CUI: C0018133
Disease: Graft-vs-Host Disease
Graft-vs-Host Disease 		0.030 Biomarker disease BEFREE Does minor histocompatibility antigen HA-1 disparity affect the occurrence of graft-versus-host disease in tunisian recipients of hematopoietic stem cells? 21243279 2010
CUI: C0018133
Disease: Graft-vs-Host Disease
Graft-vs-Host Disease 		0.030 Biomarker disease BEFREE Results of a previous study suggested that recipient mismatching for the minor histocompatibility antigen HA-1 is associated with acute graft-versus-host disease (GVHD) after allogeneic marrow transplantation. 10515896 1999
CUI: C0018133
Disease: Graft-vs-Host Disease
Graft-vs-Host Disease 		0.030 GeneticVariation disease BEFREE A mismatch of minor histocompatibility antigen HA-1 can cause GVHD in adult recipients of allogeneic bone marrow from HLA-identical donors. 8532022 1996
CUI: C0856825
Disease: Acute GVH disease
Acute GVH disease 		0.020 Biomarker disease BEFREE Correlation between disparity for the minor histocompatibility antigen HA-1 and the development of acute graft-versus-host disease after allogeneic marrow transplantation. 10515896 1999
CUI: C0856825
Disease: Acute GVH disease
Acute GVH disease 		0.020 Biomarker disease BEFREE Recipient mismatching for the minor histocompatibility antigen HA-1 has been associated with acute graft-versus-host disease after allogeneic marrow transplantation. 9820595 1998
CUI: C0025202
Disease: melanoma
melanoma 		0.010 Biomarker disease BEFREE To investigate the function of HMHA1 and its encode protein HA-1 in melanoma. 28939173 2017
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion 		0.010 Biomarker phenotype BEFREE Moreover, silencing HMHA1 not only significantly increased cell apoptosis but also suppressed cell migration and invasion. 28939173 2017
CUI: C0867389
Disease: Chronic graft-versus-host disease
Chronic graft-versus-host disease 		0.010 Biomarker disease BEFREE A univariate logistic regression model analysis showed that only acute graft-versus-host disease may be affected by recipient MiHAg-HA-1 disparity (p: 0.041, OR: 6.727), while chronic graft-versus-host disease correlates with both age and recipient/donor sex mismatch (p: 0.014, OR: 8.556 and p: 0.033, OR: 8.664, respectively). 21243279 2010
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm 		0.010 AlteredExpression group BEFREE Here, we investigated the transcriptional regulation of HA-1 gene expression in cancer. 19096014 2009
CUI: C0151449
Disease: Primary Sjögren's syndrome
Primary Sjögren's syndrome 		0.010 GeneticVariation disease BEFREE Homozygosity for the 168His variant of the minor histocompatibility antigen HA-1 is associated with reduced risk of primary Sjögren's syndrome. 15593299 2005
CUI: C1527336
Disease: Sjogren's Syndrome
Sjogren's Syndrome 		0.010 GeneticVariation disease LHGDN Homozygosity for the 168His variant of the minor histocompatibility antigen HA-1 is associated with reduced risk of primary Sjögren's syndrome. 15593299 2005
CUI: C0021400
Disease: Influenza
Influenza 		0.010 GeneticVariation disease BEFREE Direct polymerase chain reaction (PCR) amplifications of cDNA and subsequent nucleotide sequence analysis of part of the HA-1 gene of the original infecting influenza B strain and the nasal wash material from an infected volunteer were performed. 8227277 1993