Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1621958
Disease: Glioblastoma Multiforme
Glioblastoma Multiforme
0.060 Biomarker disease BEFREE Astrocytoma specimens showed lesser extent of immunostaining for IL-13Rα2 and three AP-1 factors compared to GBM specimens. 30572904 2018
CUI: C1621958
Disease: Glioblastoma Multiforme
Glioblastoma Multiforme
0.060 AlteredExpression disease BEFREE Epidermal growth factor receptor and PTEN modulate tissue factor expression in glioblastoma through JunD/activator protein-1 transcriptional activity. 19276385 2009
CUI: C1621958
Disease: Glioblastoma Multiforme
Glioblastoma Multiforme
0.060 Biomarker disease BEFREE Here, we investigated the potential roles of early growth response gene-1 (Egr-1), Sp1, nuclear factor-kappaB (NF-kappaB), activator protein-1 (AP-1), and hypoxia-inducible factor-1 (HIF-1) in the hypoxic regulation of tissue factor by glioblastoma multiforme cells in vitro. 16849552 2006
CUI: C1621958
Disease: Glioblastoma Multiforme
Glioblastoma Multiforme
0.060 AlteredExpression disease BEFREE This study reveals that an up-regulation of AP-1 factors may be a hallmark of GBM. 11778649 2001
CUI: C1621958
Disease: Glioblastoma Multiforme
Glioblastoma Multiforme
0.060 Biomarker disease BEFREE These results suggest that ERK1/2 pathway is involved in the up-regulation of VEGF expression ionizing radiation mediated by AP-1, which may lead to further neovascularization and proliferation of glioblastoma cells resistant to radiation therapy. 10885623 2000
CUI: C1621958
Disease: Glioblastoma Multiforme
Glioblastoma Multiforme
0.060 Biomarker disease BEFREE Expression of the two types of tumor necrosis factor (TNF) receptor, p55 and p75, in 12 human glioblastoma cell lines was studied. 7566386 1995