Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma
0.320 Biomarker disease BEFREE Patients with PRAME gene deletion (relative copy number of 0 or 0.5) had significantly higher frequency of PRAME nonoverexpression and lambda light chain expression than those with no deletion (p = 0.011 and 0.003).Thus, PRAME gene CNV occurs in MM. 28953414 2017
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma
0.320 Biomarker disease CTD_human The human tumor antigen PRAME is a dominant repressor of retinoic acid receptor signaling. 16179254 2005
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma
0.320 AlteredExpression disease BEFREE In this study, we have investigated the mRNA expression of the cancer germ-line genes MAGE, BAGE, GAGE, RAGE and the tumor-overexpressed gene PRAME by human myeloma cell lines and malignant plasma cells from patients with multiple myeloma (MM). 10741395 2000